MPSC SYLLABUS 2012 Part I : Pharmaceutics, Dispensing and Hospital Pharmacy

Part I : Pharmaceutics, Dispensing and Hospital Pharmacy

1. Formulations: Types, Preparation, Packaging, labeling and Storage, Various
Conventional and prolonged release drug delivery systems, per-oral and
parenteral administration, novel routes of drug administration including
pulmonary, nasal, ophthalmic, transdermal etc., concepts of drugs stability and
Shelf-life.
2. Prescription : definition, various parts of prescription, their functions, handling of
prescription, prescription charging policy, labeling requirements as per various
schedules mentioned in Drugs and Cosmetics Act and its addendum, Pharmacy
Act 1948, Drug Price Control Order as per regulatory requirements, Narcotic &
Psychotropic substances Act and Rules.
3. Posology : Definition, factors affecting dose selection, Calculation of doses for
paediatric and geriatric patients.
4. Study of various pharmacopoeias, monographs and various quality control tests
mentioned in the monographs- I.P., U.S.P., E.P., B.P.
5. Sterile Products –their manufacturing and quality Control, Methods of Sterlization
and validation thereof, Test for Sterility, Test for pyrogens, concept of asepsis
and maintenance of aseptic conditions, Central Sterile Supply Department
(CSSD) and its functioning.
Microbiological Media : Preparation and Sterilization.
Surgical dressings : Properties, sterilization, standards and tests for sterility.
Ligatures and Sutures : Absorbable and non-absorbable, preparations,
standards,and tests for sterility.
6. Hospital and Drug Store : Layout, designs. staff, materials-coding and stocking
including storage conditions. Legal requirements, maintenance of various
registers. Use of Computers for day to day record keeping. Inventory control
concept of EOQ (Economic Order Quantity ) & Purchase policy. Drug distribution
systems in hospitals- Dispensing to in-patients & out-patients. Safe use of drugs
in hospitals.
7. Clinical Pharmacy - Drug & poison information services & its management:
Patient Counseling, Patient information leaflets, patient medication adherence,
drug-drug, drug-food interactions, adverse drug reactions. Use of softwares and
databases for monitoring drug interactions, and adverse drug reactions and
idiosyncratic reactions.